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Table 1 Electrophysiological characterization of action potentials recorded from isolated cells.

From: Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

Action potentials (n = 41) Interval (ms) MDP (mV) Peak (mV) Amp (mV) dV/dtmax (mV) APD30 (ms) APD40 (ms) APD70 (ms) APD80 (ms) APD30-40/ APD70-80
Central SAN-like (n = 21) 400.0 ± 6.9 –40.4 ± 4.2 7.3 ± 0.9 47.8 ± 3.5 1.0 ± 0.1 139.0 ± 9.7 162.3 ± 11.1 173.7 ± 11.9 196.3 ± 13.4 1.0 ± 0.1
Atrial-like (n = 15) 476.6 ± 22.3 –77.2 ± 1.2 22.2 ± 1.3 99.4 ± 0.7 27.7 ± 1.1 77.4 ± 1.7 89.3 ± 2.0 107.2 ± 2.4 131.0 ± 2.9 1.1 ± 0.2
Peripheral SAN-like (n = 5) 406.4 ± 7.9 –79.4 ± 22.2 27.5 ± 3.0 106.9 ± 2.2 4.9 ± 0.4 71.3 ± 3.5 83.7 ± 3.9 100.5 ± 4.7 112.1 ± 2.9 1.1 ± 0.1
  1. Data are provided as means ± SEM
  2. Amp amplitude, APD AP duration, dV/dt max maximal rate of depolarization, Interval beating rate interval, MDP maximum diastolic potential, Peak peak voltage, SAN sinoatrial node