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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: VEGF promotes endothelial progenitor cell differentiation and vascular repair through connexin 43

Fig. 5

VEGF pretreatment before EPC transplantation promotes reendothelialization and inhibits neointimal formation through Cx43. a EPC transplantation promoted reendothelialization, which was further enhanced by VEGF stimulation. However, the silencing of Cx43 attenuated neointimal formation. b Quantitative analysis of reendothelialization (n = 3). c EPC transplantation inhibited neointimal proliferation, which was further enhanced by VEGF pretreatment. However, the silencing of Cx43 increased neointimal formation compared to the EPC + VEGF group. Scale bar = 100 μm. d Quantitative analysis of intimal proliferation (n = 3). **p < 0.01

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