Fig. 6

Changes of inflammatory cytokine levels in mouse lung lysate on PND14 (n = 6–8). a There was no difference in GM-CSF levels across all the groups. b Level of RANTES was significantly increased in the late but not the early hAEC treatment group compared to control and injury groups. c IL-1β level was increased in the injured group, and was significantly reduced to control levels by early hAEC treatment. d–f Levels of LIF (d), MIP-2 (e) and MCP-1 (f) were significantly increased in the injured group, but were reduced in both early and late treatment groups. Data expressed as mean ± standard error of mean (SEM). Statistical significance determined with one-way ANOVA accompanied by the Bonferroni post-hoc test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. hAEC human amnion epithelial cell, IL interleukin, LIF leukemia inhibitory factor, MIP macrophage inflammatory protein, MCP monocyte chemoattractant protein