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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration

Fig. 1

a Summary of primary endocrine function and expression patterns of PDX1, NEUROG3, and MAFA during mouse and human embryonic development. b Schematic of interaction of PDX1, NEUROG3, and MAFA in the activation of mouse insulin promoter. E1–E13 mouse embryonic day 1 to day 13, P1–P7 mouse postnatal day 1 to day 7, W0–W12 gestational week 1 to week 12, MAFA V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, NEUROG3 Neurogenin 3, PDX1 pancreas/duodenum homeobox protein 1

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