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Table 1 Lung inflammation: total number of cells, number of mononuclear and polymorphonuclear cells in lung tissue

From: Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

  MN (%) PMN (%) Total (%)
Lung parenchyma
 C-Sal 35.8 ± 3.3 5.8 ± 1.6 41.6 ± 3.1
 C-BMMC-healthy 37.0 ± 4.3 5.2 ± 2.3 42.2 ± 5.1
 C-BMMC-sil 33.1 ± 3.1 6.0 ± 1.9 39.1 ± 3.8
 SIL-Sal 42.6 ± 3.3* 8.2 ± 2.3 50.9 ± 2.9*
 SIL- BMMC-healthy 38.3 ± 4.4# 5.1 ± 2.8# 43.3 ± 4.2#
 SIL- BMMC-sil 35.3 ± 2.1# 5.8 ± 3.3 41.2 ± 4.2#
Granuloma
 SIL-Sal 38.8 ± 1.5 11.3 ± 2.3 50.1 ± 2.0
 SIL- BMMC-healthy 36.2 ± 2.8 7.2 ± 3.2# 43.5 ± 4.3#
 SIL- BMMC-sil 34.2 ± 2.5# 6.8 ± 2.7# 41.0 ± 3.7#
  1. Control (C) and silicotic (SIL) mice received saline (50 μL) or silica (20 mg silica/50 μL saline) (Sal) intratracheally. C and SIL animals were treated with bone marrow mononuclear cells (BMMCs) (2 × 106 cells) derived from healthy or silicotic (sil) donors. MN mononuclear cells, PMN polymorphonuclear cells, total total cellularity. Values are means ± SD. N = 10 animals per group. *Significantly different from C-Sal (P < 0.05). #Significantly different from SIL-Sal (P < 0.05)