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Table 1 Lung inflammation: total number of cells, number of mononuclear and polymorphonuclear cells in lung tissue

From: Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

 

MN (%)

PMN (%)

Total (%)

Lung parenchyma

 C-Sal

35.8 ± 3.3

5.8 ± 1.6

41.6 ± 3.1

 C-BMMC-healthy

37.0 ± 4.3

5.2 ± 2.3

42.2 ± 5.1

 C-BMMC-sil

33.1 ± 3.1

6.0 ± 1.9

39.1 ± 3.8

 SIL-Sal

42.6 ± 3.3*

8.2 ± 2.3

50.9 ± 2.9*

 SIL- BMMC-healthy

38.3 ± 4.4#

5.1 ± 2.8#

43.3 ± 4.2#

 SIL- BMMC-sil

35.3 ± 2.1#

5.8 ± 3.3

41.2 ± 4.2#

Granuloma

 SIL-Sal

38.8 ± 1.5

11.3 ± 2.3

50.1 ± 2.0

 SIL- BMMC-healthy

36.2 ± 2.8

7.2 ± 3.2#

43.5 ± 4.3#

 SIL- BMMC-sil

34.2 ± 2.5#

6.8 ± 2.7#

41.0 ± 3.7#

  1. Control (C) and silicotic (SIL) mice received saline (50 μL) or silica (20 mg silica/50 μL saline) (Sal) intratracheally. C and SIL animals were treated with bone marrow mononuclear cells (BMMCs) (2 × 106 cells) derived from healthy or silicotic (sil) donors. MN mononuclear cells, PMN polymorphonuclear cells, total total cellularity. Values are means ± SD. N = 10 animals per group. *Significantly different from C-Sal (P < 0.05). #Significantly different from SIL-Sal (P < 0.05)