Fig. 3From: Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I studyAssessment of disc degeneration grade using T2-weighted MRI. Sagittal T2-weighted images (a, pre treatment) show increased signal intensity of the L4/5 intervertebral disc from IV to III at 6Â months (b) and 12Â months (c), suggesting an increase of water content (case 1)Back to article page