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Table 3 Comparison of patients’ outcomes according to time points

From: Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study

 

VAS

ODI

 

Mean

P value_WSR

P value_paired t

Mean

P value_WSR

P value_paired t

Baseline–1 week

0.5

0.4766

0.5212

-10.6

0.0977

0.00489

Baseline–1 month

1.9

0.0098

0.0044

11.6

0.002

0.0014

Baseline–3 months

2.15

0.0156

0.014

11.09

0.0117

0.006

Baseline–6 months

3.3

0.0039

0.0008

21.52

0.002

0.0016

Baseline–9 months

3.4

0.0039

0.0012

22.72

0.002

0.0002

Baseline–12 months

3.6

0.002

0.0003

26.02

0.002

0.0004

Baseline–mean of each visit

2.475

0.0039

0.001

13.725

0.002

0.0018

  1. VAS visual analogue scale, ODI Oswestry Disability Index, WSR Wilcoxon signed-rank test