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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice

Fig. 3

TXN mitigates TBI-induced suppression of HSCs in mice. Mice were irradiated with 7.25 Gy and then treated with saline or thioredoxin (TXN) as described in the text. The frequency of HSCs in bone marrow was analyzed by flow cytometry; a percentage of KSL cells and b the absolute number of KSL cells/femur; c percentage of SLAM + KSL (SLAMKSL) and d the absolute number of SLAM + KSL cells/femur. Data are shown as the mean ± SD. *P < 0.05. KSL c-Kit+Sca-1+Lin–, n.s. not significant, TBI total body irradiation

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