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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: The similarities between smDCs and regDCs in alleviating the immune injury caused by transplantation of hepatocytes differentiated from ESCs

Fig. 5

CD3+ T-lymphocyte infiltration and inflammatory response in transplant tissues receiving hepatocytes from livers of 129 mice and ESCs of 129 mice. Transplant tissues receiving hepatocytes from the livers of 129 mice (a) showed stronger CD3+ T-lymphocyte infiltration and a more severe inflammatory response than those receiving hepatocytes derived from ESCs (b). At the same time, lower levels of inflammatory cytokines such as IL-2 and higher levels of inhibitory cytokines including IL-10 and TGF-β were seen in transplant tissues receiving hepatocytes derived from ESCs compared with those receiving hepatocytes from the livers of 129 mice (c). ESC embryonic stem cell, H1 tissues receiving hepatocytes from the livers of 129 mice, H2 tissues receiving hepatocytes derived from ESCs, IL interleukin, TGF transforming growth factor

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