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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Substance P and patterned silk biomaterial stimulate periodontal ligament stem cells to form corneal stroma in a bioengineered three-dimensional model

Fig. 2

PDLSCs differentiate into keratocytes with induction medium. Keratocyte differentiation medium was used to differentiate PDLSCs towards keratocytes for 7 and 14 days. The mRNA levels of LUM (a), KERA (b), ALDH3A1 (c), ALDH1A1 (d), COL I (e), TAC1 (f), and TACR1 (g) were evaluated by qPCR. Representative results are shown from PDLSCs derived from two different individuals. Levels at day (d)0 were set as 1. The expression was compared between d0 and d7, d0 and d14, and d14 and primary in-vitro cultured normal keratocytes. *p < 0.05, **p < 0.001. N.S. not significant

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