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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue

Fig. 6

Ectopic bone formation of ATSCs and BMSCs in nude mice. a, ATSCs and BMSCs were loaded onto sterilized porous calcium phosphate restorable granules, then implanted subcutaneously into the dorsal surfaces of nude mice. Transplants were harvested 8 weeks later for histological examination. Sections stained with routine hematoxylin and eosin (HE) and immunohistochemical (IHC) staining with anti-OCN antibody. b, The bone formation area were measured and there were significantly more bone formation in the BMSC group, *p,<0.05. ATSC: adipose tissue-derived MSC, BMSC: bone marrow-derived MSC, MSC: mesenchymal stem cells, NB: new bone tissue, OCN: Osteocalcin

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