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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Celastrol improves self-renewal and differentiation of human tendon-derived stem cells by suppressing Smad7 through hypoxia

Fig. 2

Celastrol improves the differentiation potential of hTSCs. a At day 14 after differentiation induction in the absence (control) or presence of 2 μM celastrol, the extent of adipogenesis, chondrogenesis, and osteogenesis was evaluated by Oil Red O, Alcian Blue, and Alizarin Red S staining assays, respectively. b At day 14 after differentiation induction in the absence (control) or presence of 2 μM celastrol, the extent of adipogenesis, chondrogenesis, and osteogenesis were evaluated by mRNA levels of the adipogenic marker PPARγ, the chondrogenic marker Sox9, and the osteogenic marker Runx2. Data aere shown as mean ± SD. Student’s t test was utilized for pairwise comparison. *p < 0.05, **p < 0.01, versus control

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Stem Cell Research & Therapy

ISSN: 1757-6512