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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Evaluating the oxysterol combination of 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol in periodontal regeneration using periodontal ligament stem cells and alveolar bone healing models

Fig. 5

Effect of oxysterols on LXR and Hh signaling. Cells incubated with SS at different concentrations (0.5, 1, and 5 μM). a Protein levels of LXRα (50 kDa) and LXRβ (56 kDa). b mRNA expression of LXRα, LXRβ, and ABCA1. c Protein levels of Smo (85 kDa) and Gli1 (118 kDa). Values reported as means ± SD of four independent experiments. *P < 0.05 vs control value. ABCA1 ATP-binding cassette transporter A1, Hh Hedgehog, LXR liver X receptor, Smo Smoothened

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