Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Evaluating the oxysterol combination of 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol in periodontal regeneration using periodontal ligament stem cells and alveolar bone healing models

Fig. 8

Effect of oxysterols or BMP-2 on alveolar bone regeneration. a Color-coded μCT images of extraction sockets in the control, BMP-2, and SS groups 15 days after tooth extraction. Purple area in the sockets (indicated by white arrows) represents newly formed bone (scale bar, 2 mm). b Newly formed bone volume in sockets (%) measured three-dimensionally (mean ± SD). c Protein levels of COLIA, ALP, RUNX2, and OCN determined to confirm alveolar bone regeneration using western blotting analysis. ALP alkaline phosphatase, BMP‐2 bone morphogenetic protein‐2, Con control, OCN osteocalcin, RUNX2 Runt-related transcription factor 2, SS 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512