Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Mesenchymal stem cell-derived extracellular vesicles for kidney repair: current status and looming challenges

Fig. 2

Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are taken up by renal proximal and distal tubular cells, macrophages, and endothelial cells. MSC-derived EVs transfer their protein, mRNA, and microRNA content into recipient cells. This in turn modulates several pathways involved in the pathophysiology of renal disease, including vascular rarefaction, inflammation, oxidative stress, fibrosis, extracellular matrix remodeling, apoptosis, and cell proliferation. This figure is original for this article

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512