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Table 1 Clinical studies testing the efficacy of MSCs in AKI and CKD

From: Mesenchymal stem cell-derived extracellular vesicles for kidney repair: current status and looming challenges

Condition ID Title Link Status
AKI NCT01275612 Mesenchymal stem cells in cisplatin-induced acute renal failure in patients with solid organ cancers https://clinicaltrials.gov/ct2/show/NCT01275612 Recruiting
NCT00733876 Allogeneic multipotent stromal cell treatment for acute kidney injury following cardiac surgery https://clinicaltrials.gov/ct2/show/NCT00733876 Completed
NCT01602328 A study to evaluate the safety and efficacy of AC607 for the treatment of kidney injury in cardiac surgery subjects https://clinicaltrials.gov/ct2/show/NCT01602328 Terminated
CKD NCT02166489 Mesenchymal stem cells transplantation in patients with chronic renal failure due to polycystic kidney disease https://clinicaltrials.gov/ct2/show/NCT02166489 Completed
NCT01843387 Safety and efficacy of mesenchymal precursor cells in diabetic nephropathy https://clinicaltrials.gov/ct2/show/NCT01843387 Completed
NCT02266394 Hypoxia and inflammatory injury in human renovascular hypertension https://clinicaltrials.gov/ct2/show/NCT02266394 Recruiting
NCT02409940 To elucidate the effect of mesenchymal stem cells on the T-cell repertoire of the kidney transplant patients https://clinicaltrials.gov/ct2/show/NCT02409940 Ongoing
NCT00658073 Induction therapy with autologous mesenchymal stem cells for kidney allografts https://clinicaltrials.gov/ct2/show/NCT00658073 Completed
  1. AKI acute kidney injury, CKD chronic kidney disease