Skip to main content

Table 6 Experimental studies testing the efficacy of MSC-derived EVs in STN-CKD

From: Mesenchymal stem cell-derived extracellular vesicles for kidney repair: current status and looming challenges

Type of model

Species

Intervention

Administration method

Main findings

Reference

In vivo

Mouse

Allogenic bone marrow MSC-derived EVs

Intravenous

• EVs improved renal function

• Decreased renal fibrosis, inflammation, and tubular atrophy

He et al. 2012 [60]

  1. CKD chronic kidney disease, EV extracellular vesicle, MSC mesenchymal stem cell, STN subtotal nephrectomy
Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512