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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

Fig. 8

Immunohistochemistry analysis of the expression of pRSK, p-p38, p-ERK, and NF-κB in macrophages. Macrophages were prepared and immunofluorescence was used to assess the expression of (a) pRSK, (b) p-p38, (c) p-ERK, and (d) NFκB using fluorescence microscopy. TO-PRO-3-staining nuclei (blue) are also shown. Images show representative data from one of four individual experiments. pRSK, p-p38, p-ERK, and NF-κB expression increased in the macrophages treated with LPS when compared with the untreated group. This increase was reduced in the group co-cultured with mesenchymal stem cells (MSCs). n = 5, ×20 magnification

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