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Table 3 Pearson correlation coefficients determined for mean cell area and each aging-related marker

From: Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures

 

Mean cell area

PD/day

p16INK4a

p21Cip1/Waf1

SA-β-gal

Mean telomere length

Mean cell area

1.00

−0.74

0.50

0.52

0.70

-0.71

PD/day

−0.74

1.00

−0.59

−0.67

-0.80

0.89

p16INK4a

0.50

−0.59

1.00

0.52

0.66

-0.36

p21Cip1/Waf1

0.52

−0.67

0.52

1.00

0.23

-0.63

SA-β-gal

0.70

−0.80

0.66

0.23

1.00

-0.65

Mean telomere length

−0.71

0.89

−0.36

−0.63

-0.65

1.00

  1. The data were collected from long-term cultures of three donors
  2. PD population doubling, SA-β-gal senescence-associated β-galactosidase