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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Adipose tissue-derived stem cells ameliorate hyperglycemia, insulin resistance and liver fibrosis in the type 2 diabetic rats

Fig. 7

ADSC transplantation ameliorates liver fibrosis by inhibiting TGF-β1/SMAD3 signaling. a The relative mRNA expression of TGF-β1 in the liver tissues after ADSC transplantation. b Western blot analysis for TGF-β1, p-SMAD3, SMAD3, and β-actin in the liver tissues after ADSC transplantation. Relative expression of TGF-β1 (c) and p-SMAD3 (d) in the liver tissues after ADSC transplantation (n = 6 per group; *p < 0.05; **p < 0.01). ADSCs adipose tissue-derived stem cells, p-SMAD3 phosphorylation of mothers against decapentaplegic homolog 3, SMAD3 mothers against decapentaplegic homolog 3, TGF-β1 transforming growth factor beta 1

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Stem Cell Research & Therapy

ISSN: 1757-6512