Skip to main content
Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: High-throughput immunophenotypic characterization of bone marrow- and cord blood-derived mesenchymal stromal cells reveals common and differentially expressed markers: identification of angiotensin-converting enzyme (CD143) as a marker differentially expressed between adult and perinatal tissue sources

Fig. 1

Common MSC marker identification. a Marker classification according to unsupervised HCL. Heat-map expression of the 59 markers selected by HCL on both bone marrow (BM)- and cord blood (CB)-MSC samples. Antigen expression level is color coded from white (no expression) to red (strong expression). Data are presented as log2 FI (median fluorescence intensity on the isotype control). Markers are shown according to four clusters of expression (no expression: cluster 1; low expression: cluster 2; intermediate expression: cluster 3; strong expression: cluster 4), with clusters identified with different shades of gray; CB-MSC samples are shown in blue; BM-MSC samples in green; bulk samples in red; single clones in yellow. b Common MSC marker identification. Boxes extend from 25th percentile to the 75th percentile, the line in the middle represents the median value and the whiskers extend from minimum to maximum values. ISCT-positive and negative markers are shown in grey. Abbreviations: HCL, hierarchical clustering; FI, fold increase

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512