TY - JOUR AU - Zhang, C. AU - Li, W. AU - Wen, J. AU - Yang, Z. PY - 2017 DA - 2017// TI - Autophagy is involved in mouse kidney development and podocyte differentiation regulated by notch signalling JO - J Cell Mol Med VL - 21 UR - https://doi.org/10.1111/jcmm.13061 DO - 10.1111/jcmm.13061 ID - Zhang2017 ER - TY - JOUR AU - Squillaro, T. AU - Peluso, G. AU - Galderisi, U. PY - 2016 DA - 2016// TI - Clinical trials with mesenchymal stem cells: an update JO - Cell Transplant VL - 25 UR - https://doi.org/10.3727/096368915X689622 DO - 10.3727/096368915X689622 ID - Squillaro2016 ER - TY - JOUR AU - Xing, X. AU - Zhang, Z. AU - Zhong, L. AU - Ju, G. AU - Zou, X. AU - Zhu, Y. PY - 2016 DA - 2016// TI - Differentiation of human umbilical cord mesenchymal stem cells into steroidogenic cells in vitro JO - Exp Ther Med VL - 12 UR - https://doi.org/10.3892/etm.2016.3815 DO - 10.3892/etm.2016.3815 ID - Xing2016 ER - TY - JOUR AU - Nan, C. AU - Guo, L. AU - Zhao, Z. AU - Ma, S. AU - Liu, J. AU - Yan, D. PY - 2016 DA - 2016// TI - Tetramethylpyrazine induces differentiation of human umbilical cord-derived mesenchymal stem cells into neuron-like cells in vitro JO - Int J Oncol VL - 48 UR - https://doi.org/10.3892/ijo.2016.3449 DO - 10.3892/ijo.2016.3449 ID - Nan2016 ER - TY - JOUR AU - Szychlinska, M. A. AU - Castrogiovanni, P. AU - Nsir, H. AU - Rosa, M. AU - Guglielmino, C. AU - Parenti, R. PY - 2017 DA - 2017// TI - Engineered cartilage regeneration from adipose tissue derived-mesenchymal stem cells: a morphomolecular study on osteoblast, chondrocyte and apoptosis evaluation JO - Exp Cell Res VL - 357 UR - https://doi.org/10.1016/j.yexcr.2017.05.018 DO - 10.1016/j.yexcr.2017.05.018 ID - Szychlinska2017 ER - TY - JOUR AU - Zhang, Y. AU - Yang, J. AU - Zhang, P. AU - Liu, T. AU - Xu, J. AU - Fan, Z. PY - 2016 DA - 2016// TI - Calcitonin gene-related peptide is a key factor in the homing of transplanted human MSCs to sites of spinal cord injury JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep27724 DO - 10.1038/srep27724 ID - Zhang2016 ER - TY - JOUR AU - Huang, P. Y. AU - Shih, Y. H. AU - Tseng, Y. J. AU - Ko, T. L. AU - Fu, Y. S. AU - Lin, Y. Y. PY - 2016 DA - 2016// TI - Xenograft of human umbilical mesenchymal stem cells from Wharton’s jelly as a potential therapy for rat pilocarpine-induced epilepsy JO - Brain Behav Immun VL - 54 UR - https://doi.org/10.1016/j.bbi.2015.12.021 DO - 10.1016/j.bbi.2015.12.021 ID - Huang2016 ER - TY - JOUR AU - Gardner, O. F. W. AU - Musumeci, G. AU - Neumann, A. J. AU - Eglin, D. AU - Archer, C. W. AU - Alini, M. PY - 2017 DA - 2017// TI - Asymmetrical seeding of MSCs into fibrin-poly(ester-urethane) scaffolds and its effect on mechanically induced chondrogenesis JO - J Tissue Eng Regen Med VL - 11 UR - https://doi.org/10.1002/term.2194 DO - 10.1002/term.2194 ID - Gardner2017 ER - TY - JOUR AU - Hou, J. AU - Han, Z. AU - Jing, Y. AU - Yang, X. AU - Zhang, S. AU - Sun, K. PY - 2013 DA - 2013// TI - Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells JO - Cell Death Dis VL - 4 UR - https://doi.org/10.1038/cddis.2013.338 DO - 10.1038/cddis.2013.338 ID - Hou2013 ER - TY - JOUR AU - Sbrana, F. V. AU - Cortini, M. AU - Avnet, S. AU - Perut, F. AU - Columbaro, M. AU - Milito, A. PY - 2016 DA - 2016// TI - The role of autophagy in the maintenance of stemness and differentiation of mesenchymal stem cells JO - Stem Cell Rev VL - 12 UR - https://doi.org/10.1007/s12015-016-9690-4 DO - 10.1007/s12015-016-9690-4 ID - Sbrana2016 ER - TY - JOUR AU - Rodolfo, C. AU - Bartolomeo, S. AU - Cecconi, F. PY - 2016 DA - 2016// TI - Autophagy in stem and progenitor cells JO - Cell Mol Life Sci VL - 73 UR - https://doi.org/10.1007/s00018-015-2071-3 DO - 10.1007/s00018-015-2071-3 ID - Rodolfo2016 ER - TY - JOUR AU - Li, B. AU - Duan, P. AU - Li, C. AU - Jing, Y. AU - Han, X. AU - Yan, W. PY - 2016 DA - 2016// TI - Role of autophagy on bone marrow mesenchymal stem cell proliferation and differentiation into neurons JO - Mol Med Rep VL - 13 UR - https://doi.org/10.3892/mmr.2015.4673 DO - 10.3892/mmr.2015.4673 ID - Li2016 ER - TY - JOUR AU - Wan, Y. AU - Zhuo, N. AU - Li, Y. AU - Zhao, W. AU - Jiang, D. PY - 2017 DA - 2017// TI - Autophagy promotes osteogenic differentiation of human bone marrow mesenchymal stem cell derived from osteoporotic vertebrae JO - Biochem Biophys Res Commun VL - 488 UR - https://doi.org/10.1016/j.bbrc.2017.05.004 DO - 10.1016/j.bbrc.2017.05.004 ID - Wan2017 ER - TY - STD TI - Szychlinska MA, Stoddart MJ, D’Amora U, Ambrosio L, Alini MP, Musumeci G. Mesenchymal stem cell-based cartilage regeneration approach and cell senescence: can we manipulate cell aging and function? Tissue Eng Part B Rev. 2017. https://doi.org/10.1089/ten.TEB.2017.0083. ID - ref14 ER - TY - JOUR AU - Zheng, Y. AU - Hu, C. J. AU - Zhuo, R. H. AU - Lei, Y. S. AU - Han, N. N. AU - He, L. PY - 2014 DA - 2014// TI - Inhibition of autophagy alleviates the senescent state of rat mesenchymal stem cells during long-term culture JO - Mol Med Rep VL - 10 UR - https://doi.org/10.3892/mmr.2014.2624 DO - 10.3892/mmr.2014.2624 ID - Zheng2014 ER - TY - STD TI - Karch J, Schips TG, Maliken BD, Brody MJ, Sargent MA, Kanisciak O, et al. Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak. Elife. 2017;6. https://doi.org/10.7554/eLife.30543. ID - ref16 ER - TY - JOUR AU - Musumeci, G. AU - Castrogiovanni, P. AU - Trovato, F. M. AU - Weinberg, A. M. AU - Al-Wasiyah, M. K. AU - Alqahtani, M. H. PY - 2015 DA - 2015// TI - Biomarkers of chondrocyte apoptosis and autophagy in osteoarthritis JO - Int J Mol Sci VL - 16 UR - https://doi.org/10.3390/ijms160920560 DO - 10.3390/ijms160920560 ID - Musumeci2015 ER - TY - JOUR AU - Zhang, Q. AU - Yang, Y. -. J. AU - Wang, H. AU - Dong, Q. -. T. AU - Wang, T. -. J. AU - Qian, H. -. Y. PY - 2012 DA - 2012// TI - Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway JO - Stem Cells Dev VL - 21 UR - https://doi.org/10.1089/scd.2011.0684 DO - 10.1089/scd.2011.0684 ID - Zhang2012 ER - TY - JOUR AU - Yang, H. AU - Xie, Z. H. AU - Wei, L. F. AU - Yang, H. N. AU - Yang, S. N. AU - Zhu, Z. Y. PY - 2013 DA - 2013// TI - Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model JO - Stem Cell Res Ther VL - 4 UR - https://doi.org/10.1186/scrt227 DO - 10.1186/scrt227 ID - Yang2013 ER - TY - JOUR AU - Puzzo, D. AU - Loreto, C. AU - Giunta, S. AU - Musumeci, G. AU - Frasca, G. AU - Podda, M. V. PY - 2014 DA - 2014// TI - Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice JO - Neurobiol Aging VL - 35 UR - https://doi.org/10.1016/j.neurobiolaging.2013.09.002 DO - 10.1016/j.neurobiolaging.2013.09.002 ID - Puzzo2014 ER - TY - JOUR AU - Choi, S. S. AU - Lee, S. -. R. AU - Kim, S. U. AU - Lee, H. J. PY - 2014 DA - 2014// TI - Alzheimer’s disease and stem cell therapy JO - Exp Neurobiol VL - 23 UR - https://doi.org/10.5607/en.2014.23.1.45 DO - 10.5607/en.2014.23.1.45 ID - Choi2014 ER - TY - JOUR AU - Lee, H. J. AU - Lee, J. K. AU - Lee, H. AU - Carter, J. E. AU - Chang, J. W. AU - Oh, W. PY - 2012 DA - 2012// TI - Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer’s disease mouse model through modulation of neuroinflammation JO - Neurobiol Aging VL - 33 UR - https://doi.org/10.1016/j.neurobiolaging.2010.03.024 DO - 10.1016/j.neurobiolaging.2010.03.024 ID - Lee2012 ER - TY - JOUR AU - Kim, J. AU - Kim, D. AU - Kim, J. AU - Lee, D. AU - Jeon, H. AU - Kwon, S. PY - 2012 DA - 2012// TI - Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques JO - Cell Death Differ VL - 19 UR - https://doi.org/10.1038/cdd.2011.140 DO - 10.1038/cdd.2011.140 ID - Kim2012 ER - TY - JOUR AU - Oh, S. H. AU - Kim, H. N. AU - Park, H. -. J. AU - Shin, J. Y. AU - Lee, P. H. PY - 2015 DA - 2015// TI - Mesenchymal stem cells increase hippocampal neurogenesis and neuronal differentiation by enhancing the Wnt signaling pathway in an Alzheimer’s disease model JO - Cell Transplant VL - 24 UR - https://doi.org/10.3727/096368914X679237 DO - 10.3727/096368914X679237 ID - Oh2015 ER - TY - JOUR AU - Yang, H. AU - Xie, Z. AU - Wei, L. AU - Yang, H. AU - Yang, S. AU - Zhu, Z. PY - 2013 DA - 2013// TI - Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AbetaPP/PS1 transgenic mouse model JO - Stem Cell Res Ther VL - 4 UR - https://doi.org/10.1186/scrt227 DO - 10.1186/scrt227 ID - Yang2013 ER - TY - JOUR AU - Wang, H. AU - Gao, N. AU - Li, Z. AU - Yang, Z. AU - Zhang, T. PY - 2016 DA - 2016// TI - Autophagy alleviates melamine-induced cell death in PC12 cells via decreasing ROS level JO - Mol Neurobiol VL - 53 UR - https://doi.org/10.1007/s12035-014-9073-2 DO - 10.1007/s12035-014-9073-2 ID - Wang2016 ER - TY - JOUR AU - Zhang, M. AU - Du, Y. AU - Lu, R. AU - Shu, Y. AU - Zhao, W. AU - Li, Z. PY - 2016 DA - 2016// TI - Cholesterol retards senescence in bone marrow mesenchymal stem cells by modulating autophagy and ROS/p53/p21Cip1/Waf1 pathway JO - Oxid Med Cell Longev VL - 2016 ID - Zhang2016 ER - TY - JOUR AU - Li, Z. Y. AU - Chung, Y. H. AU - Shin, E. J. AU - Dang, D. K. AU - Jeong, J. H. AU - Ko, S. K. PY - 2017 DA - 2017// TI - YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by beta-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2 JO - J Neuroinflammation VL - 14 UR - https://doi.org/10.1186/s12974-017-0866-x DO - 10.1186/s12974-017-0866-x ID - Li2017 ER - TY - JOUR AU - Zhou, L. AU - Liu, J. AU - Dong, D. AU - Wei, C. AU - Wang, R. PY - 2017 DA - 2017// TI - Dynamic alteration of neprilysin and endothelin-converting enzyme in age-dependent APPswe/PS1dE9 mouse model of Alzheimer’s disease JO - Am J Transl Res VL - 9 ID - Zhou2017 ER - TY - JOUR AU - Deacon, R. M. AU - Rawlins, J. N. P. PY - 2006 DA - 2006// TI - T-maze alternation in the rodent JO - Nat Protoc VL - 1 UR - https://doi.org/10.1038/nprot.2006.2 DO - 10.1038/nprot.2006.2 ID - Deacon2006 ER - TY - JOUR AU - Spellman, T. AU - Rigotti, M. AU - Ahmari, S. E. AU - Fusi, S. AU - Gogos, J. A. AU - Gordon, J. A. PY - 2015 DA - 2015// TI - Hippocampal-prefrontal input supports spatial encoding in working memory JO - Nature VL - 522 UR - https://doi.org/10.1038/nature14445 DO - 10.1038/nature14445 ID - Spellman2015 ER - TY - JOUR AU - Li, Z. AU - Hao, S. AU - Yin, H. AU - Gao, J. AU - Yang, Z. PY - 2016 DA - 2016// TI - Autophagy ameliorates cognitive impairment through activation of PVT1 and apoptosis in diabetes mice JO - Behav Brain Res VL - 305 UR - https://doi.org/10.1016/j.bbr.2016.03.023 DO - 10.1016/j.bbr.2016.03.023 ID - Li2016 ER - TY - JOUR AU - Li, W. AU - Yuan, H. AU - Yu, Y. AU - Cheong, Y. K. AU - Ren, G. AU - Yang, Z. PY - 2017 DA - 2017// TI - Etidronate rescues cognitive deficits through improving synaptic transmission and suppressing apoptosis in 2-vessel occlusion model rats JO - J Neurochem VL - 140 UR - https://doi.org/10.1111/jnc.13904 DO - 10.1111/jnc.13904 ID - Li2017 ER - TY - JOUR AU - Nigris, F. AU - Schiano, C. AU - Infante, T. AU - Napoli, C. PY - 2012 DA - 2012// TI - CXCR4 inhibitors: tumor vasculature and therapeutic challenges JO - Recent Pat Anticancer Drug Discov VL - 7 UR - https://doi.org/10.2174/157489212801820039 DO - 10.2174/157489212801820039 ID - Nigris2012 ER - TY - JOUR AU - Sarlak, G. AU - Vincent, B. PY - 2016 DA - 2016// TI - The roles of the stem cell-controlling Sox2 transcription factor: from neuroectoderm development to Alzheimer’s disease? JO - Mol Neurobiol VL - 53 UR - https://doi.org/10.1007/s12035-015-9123-4 DO - 10.1007/s12035-015-9123-4 ID - Sarlak2016 ER - TY - STD TI - Apostolopoulou M, Kiehl TR, Winter M, Cardenas De La Hoz E, Boles NC, Bjornsson CS, et al. Non-monotonic changes in progenitor cell behavior and gene expression during aging of the adult V-SVZ neural stem cell niche. Stem Cell Reports. 2017. https://doi.org/10.1016/j.stemcr.2017.10.005. ID - ref36 ER - TY - STD TI - Bustos FJ, Ampuero E, Jury N, Aguilar R, Falahi F, Toledo J, et al. Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice. Brain. 2017. https://doi.org/10.1093/brain/awx272. ID - ref37 ER - TY - JOUR AU - Guan, J. L. AU - Simon, A. K. AU - Prescott, M. AU - Menendez, J. A. AU - Liu, F. AU - Wang, F. PY - 2013 DA - 2013// TI - Autophagy in stem cells JO - Autophagy VL - 9 UR - https://doi.org/10.4161/auto.24132 DO - 10.4161/auto.24132 ID - Guan2013 ER - TY - JOUR AU - Salemi, S. AU - Yousefi, S. AU - Constantinescu, M. A. AU - Fey, M. F. AU - Simon, H. -. U. PY - 2012 DA - 2012// TI - Autophagy is required for self-renewal and differentiation of adult human stem cells JO - Cell Res VL - 22 UR - https://doi.org/10.1038/cr.2011.200 DO - 10.1038/cr.2011.200 ID - Salemi2012 ER - TY - JOUR AU - Oliver, L. AU - Hue, E. AU - Priault, M. AU - Vallette, F. M. PY - 2012 DA - 2012// TI - Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells JO - Stem Cells Dev VL - 21 UR - https://doi.org/10.1089/scd.2012.0124 DO - 10.1089/scd.2012.0124 ID - Oliver2012 ER - TY - JOUR AU - Sbrana, F. V. AU - Cortini, M. AU - Avnet, S. AU - Perut, F. AU - Columbaro, M. AU - Milito, A. PY - 2016 DA - 2016// TI - The role of autophagy in the maintenance of stemness and differentiation of mesenchymal stem cells JO - Stem Cell Rev Rep VL - 12 UR - https://doi.org/10.1007/s12015-016-9690-4 DO - 10.1007/s12015-016-9690-4 ID - Sbrana2016 ER - TY - JOUR AU - Sanchez, C. G. AU - Penfornis, P. AU - Oskowitz, A. Z. AU - Boonjindasup, A. G. AU - Cai, D. Z. AU - Dhule, S. S. PY - 2011 DA - 2011// TI - Activation of autophagy in mesenchymal stem cells provides tumor stromal support JO - Carcinogenesis VL - 32 UR - https://doi.org/10.1093/carcin/bgr029 DO - 10.1093/carcin/bgr029 ID - Sanchez2011 ER - TY - JOUR AU - Shin, J. Y. AU - Park, H. J. AU - Kim, H. N. AU - Oh, S. H. AU - Bae, J. S. AU - Ha, H. J. PY - 2014 DA - 2014// TI - Mesenchymal stem cells enhance autophagy and increase beta-amyloid clearance in Alzheimer disease models JO - Autophagy VL - 10 UR - https://doi.org/10.4161/auto.26508 DO - 10.4161/auto.26508 ID - Shin2014 ER - TY - STD TI - Kasza A, Penke B, Frank Z, Bozso Z, Szegedi V, Hunya A, et al. Studies for improving a rat model of alzheimer’s disease: ICV administration of well-characterized beta-amyloid 1-42 oligomers induce dysfunction in spatial memory. Molecules. 2017;22. https://doi.org/10.3390/molecules22112007. ID - ref44 ER - TY - STD TI - Huang W-H, Chao H-W, Tsai L-Y, Chung M-H, Huang Y-S. Elevated activation of CaMKII alpha in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation. Frontiers in Cellular Neuroscience. 2014;8:367. ID - ref45 ER - TY - JOUR AU - Piaceri, I. AU - Nacmias, B. AU - Sorbi, S. PY - 2012 DA - 2012// TI - Genetics of familial and sporadic Alzheimer’s disease JO - Front Biosci (Elite Ed) VL - 5 ID - Piaceri2012 ER - TY - JOUR AU - Malinow, R. PY - 2012 DA - 2012// TI - New developments on the role of NMDA receptors in Alzheimer’s disease JO - Curr Opin Neurobiol VL - 22 UR - https://doi.org/10.1016/j.conb.2011.09.001 DO - 10.1016/j.conb.2011.09.001 ID - Malinow2012 ER - TY - JOUR AU - Viana Silva, S. AU - Haberl, M. G. AU - Zhang, P. AU - Bethge, P. AU - Lemos, C. AU - Goncalves, N. PY - 2016 DA - 2016// TI - Early synaptic deficits in the APP/PS1 mouse model of Alzheimer’s disease involve neuronal adenosine A2A receptors JO - Nat Commun VL - 7 UR - https://doi.org/10.1038/ncomms11915 DO - 10.1038/ncomms11915 ID - Viana Silva2016 ER - TY - JOUR AU - Capasso, S. AU - Alessio, N. AU - Squillaro, T. AU - Bernardo, G. AU - Melone, M. A. AU - Cipollaro, M. PY - 2015 DA - 2015// TI - Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells JO - Oncotarget VL - 6 UR - https://doi.org/10.18632/oncotarget.6277 DO - 10.18632/oncotarget.6277 ID - Capasso2015 ER -