Fig. 4

The effect of human umbilical cord mesenchymal stem cell (huMSC) transplantation on Aβ clearance in the cortex and hippocampus. a Aβ was detected by immunofluorescence staining and quantitative analysis in the cortex and hippocampus region (arrows indicate Aβ plaques). b Representative cropped Western blots and statistical analysis of amyloid precursor protein (APP) and presenilin 1 (PS1) in the cortex and hippocampus region. All data are expressed as mean ± SEM, n = 3 per group. Data were generated from three independent experiments. *P < 0.05, **P < 0.01, vs. AD-Veh; ^#P < 0.05, ^##P < 0.01, vs. huMSCs-shNC