Skip to main content
Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro

Fig. 1

A Histomorphological analysis of the kidney in each group 14 days postoperatively. (a–d) H&E staining. (e–h) PAS staining. (i–l) Masson’s trichrome staining. B Results of renal tubular histology score. Loss of brush border, tubular dilation, and apoptosis/necrosis of tubular cells were assessed. C Area of renal interstitial fibrosis in each group. hucMSC-CM transplantation could significantly inhibit renal interstitial fibrosis in UUO kidney. Values presented as mean ± SD. UUO group compared with Sham, Control, and hucMSC-CM groups. Values statistically significant at: *P < 0.05, Sham and Control groups compared with UUO and hucMSC-CM groups; #P < 0.05. CM conditioned medium, hucMSC human umbilical cord-derived mesenchymal stem cell, UUO unilateral ureteral obstruction

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512