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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Interleukin-6/interleukin-6 receptor complex promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells

Fig. 6

IL-6 and IL-6R stimulate each other’s expression in BM-MSCs. a IL-6 secretion in BM-MSCs was increased by exogenous sIL-6R but decreased by IL-6R-neutralizing antibody during osteogenic differentiation. b Western blotting results showed that mIL-6R expression in BM-MSCs was induced by exogenous IL-6 but reduced by IL-6-neutralizing antibody. Data are presented as the means ± SD of 15 samples per group. *Indicates P < 0.05 compared to the induction group. IL-6 interleukin 6, IL-6R interleukin 6 receptor

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