Fig. 8

CS-C promotes skin reconstruction. a Immunohistochemical staining (10×, 100 μm) and b macroscopic observation of the wound areas in the control, BMSC sheets induced without curcumin (CS-N), and BMSC sheets induced by curcumin (CS-C) groups at days 3, 7, 14, 21, and 28 (n = 5 mice/group). c Statistical analysis of wound closure rate in continuous time (3, 7, 14, 21, and 28 days). d Masson’s trichrome staining (10×, 100 μm) of healing wounds in the control group, CS-N group, CS-C group, and normal group at 28 days post-operation. ANOVA: *P < 0.05, **P < 0.01, ***P < 0.001. F hair follicle, N normal site, ns not significant, S sebaceous gland, W wound site