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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model

Fig. 1

Characteristics of MSC-derived EVs. Extracellular vesicles (EVs) were isolated from the conditioned medium of porcine bone marrow-derived mesenchymal stem cells (BM-MSCs) by ultracentrifugation. Morphology and size of MSC-EVs was examined by TEM. EVs were round-shaped and approximately 100 nm in size (×25 K). Expression of mesenchymal markers on MSCs and MSC-EVs was examined by flow cytometry. MSCs expressed the mesenchymal markers CD29, CD44, and CD90, and swine leukocyte antigen (SLA)-I, but SLA-II was not expressed. Similarly to MSCs, EVs expressed the mesenchymal markers but lacked the expression of SLA-I and SLA-II (black line: isotype staining; red line: specific staining)

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Stem Cell Research & Therapy

ISSN: 1757-6512