Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications

Fig. 2

Promising methods for using MSCs as delivery vehicles. (i) Transduct MSCs with retroviral vectors that carry therapeutic RNA: capture the MSCs from the patient, modify MSCs by transduction with retroviral vectors at the first passage, culture the transducted MSCs for several days, select the cells with puromycin, expand the transducted and selected cells to the clinical necessary dose, and finally administer them to the patient. (ii) Load MSCs with nanoparticles incorporated with drugs: load chemotherapeutic agents in nanoparticles, uptake the nanoparticles with MSCs, and administer the MSCs into patients

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512