Fig. 7From: Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factorA combination of epidermal growth factor (EGF) and hepatocyte growth factor (HGF) increases the follicle numbers and elevates the hormone levels to a greater extent than using them alone after an injection into a natural ovarian aging (NOA) mouse model. a A combination of EGF and HGF increased the follicle numbers to a higher level than using them singly. b A combination of EGF and HGF increased the level of estradiol (E2) to a higher level than using them singly. c A combination of EGF and HGF increased the level of follicle-stimulating hormone (FSH) to a higher level than using them singly. d A combination of EGF and HGF increased the level of anti-mullerian hormone (AMH) to a higher level than using them singly. All the experiments were repeated three times; error bars indicate SD. *p < 0.05, **p < 0.01, versus the HGF group; #p < 0.05, ##p < 0.01, versus the EGF groupBack to article page