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Table 2 Patient data over time

From: Autologous bone marrow-derived mononuclear cell therapy in Chinese patients with critical limb ischemia due to thromboangiitis obliterans: 10-year results

   Baseline 1 year 5 years 10 years
Ulcer area (cm2) Aspirin alone 3.40 ± 0.96 P = 0.362 2.50 ± 0.80 P = 0.010 2.20 ± 0.72 P =0.007 1.82 ± 0.71 P = 0.004
Aspirin + ABMMNC 3.70 ± 1.05 0.35 ± 0.14 0.25 ± 0.08 0.00 ± 0.01
ABI Aspirin alone 0.45 ± 0.10 P = 0.607 0.53 ± 0.11 P = 0.078 0.46 ± 0.12 P =0.090 0.54 ± 0.15 P = 0.215
Aspirin + ABMMNC 0.47 ± 0.11 0.63 ± 0.12 0.61 ± 0.15 0.62 ± 0.11
Toe pressure (mmHg) Aspirin alone 20.1 ± 2.1 P = 0.724 23.8 ± 1.8 P<0.0001 23.4 ± 2.1 P<0.0001 25.2 ± 1.5 P<0.0001
Aspirin + ABMMNC 18.5 ± 1.4 48.3 ± 5.1 56.1 ± 5.4 59.8 ± 6.6
TBI Aspirin alone 0.16 ± 0.05 P = 0.584 0.19 ± 0.06 P = 0.001 0.19 ± 0.05 P<0.0001 0.20 ± 0.05 P <0.0001
Aspirin + ABMMNC 0.15 ± 0.04 0.39 ± 0.11 0.46 ± 0.12 0.49 ± 0.11
TcPO2 (mmHg) Aspirin alone 21.6 ± 5.2 P = 0.290 25.2 ± 7.2 P=0.0001 27.4 ± 5.4 P<0.0001 27.0 ± 5.1 P <0.0001
Aspirin + ABMMNC 22.3 ± 4.5 43.4 ± 5.1 49.1 ± 6.7 45.6 ± 5.4
Pain score Aspirin alone 7.98 ± 0.90 P = 0.708 5.92 ± 0.52 P<0.0001 5.61 ± 0.78 P<0.0001 5.66 ± 0.42 P <0.0001
Aspirin + ABMMNC 8.10 ± 0.86 0.84 ± 0.10 0.50 ± 0.06 0.22 ± 0.03
  1. ABI, ankle-brachial index; TBI, toe-brachial index; TcPO2, transcutaneous oxygen pressure