Baseline | 1 year | 5 years | 10 years | ||||||
---|---|---|---|---|---|---|---|---|---|
Ulcer area (cm2) | Aspirin alone | 3.40 ± 0.96 | P = 0.362 | 2.50 ± 0.80 | P = 0.010 | 2.20 ± 0.72 | P =0.007 | 1.82 ± 0.71 | P = 0.004 |
Aspirin + ABMMNC | 3.70 ± 1.05 | 0.35 ± 0.14 | 0.25 ± 0.08 | 0.00 ± 0.01 | |||||
ABI | Aspirin alone | 0.45 ± 0.10 | P = 0.607 | 0.53 ± 0.11 | P = 0.078 | 0.46 ± 0.12 | P =0.090 | 0.54 ± 0.15 | P = 0.215 |
Aspirin + ABMMNC | 0.47 ± 0.11 | 0.63 ± 0.12 | 0.61 ± 0.15 | 0.62 ± 0.11 | |||||
Toe pressure (mmHg) | Aspirin alone | 20.1 ± 2.1 | P = 0.724 | 23.8 ± 1.8 | P<0.0001 | 23.4 ± 2.1 | P<0.0001 | 25.2 ± 1.5 | P<0.0001 |
Aspirin + ABMMNC | 18.5 ± 1.4 | 48.3 ± 5.1 | 56.1 ± 5.4 | 59.8 ± 6.6 | |||||
TBI | Aspirin alone | 0.16 ± 0.05 | P = 0.584 | 0.19 ± 0.06 | P = 0.001 | 0.19 ± 0.05 | P<0.0001 | 0.20 ± 0.05 | P <0.0001 |
Aspirin + ABMMNC | 0.15 ± 0.04 | 0.39 ± 0.11 | 0.46 ± 0.12 | 0.49 ± 0.11 | |||||
TcPO2 (mmHg) | Aspirin alone | 21.6 ± 5.2 | P = 0.290 | 25.2 ± 7.2 | P=0.0001 | 27.4 ± 5.4 | P<0.0001 | 27.0 ± 5.1 | P <0.0001 |
Aspirin + ABMMNC | 22.3 ± 4.5 | 43.4 ± 5.1 | 49.1 ± 6.7 | 45.6 ± 5.4 | |||||
Pain score | Aspirin alone | 7.98 ± 0.90 | P = 0.708 | 5.92 ± 0.52 | P<0.0001 | 5.61 ± 0.78 | P<0.0001 | 5.66 ± 0.42 | P <0.0001 |
Aspirin + ABMMNC | 8.10 ± 0.86 | 0.84 ± 0.10 | 0.50 ± 0.06 | 0.22 ± 0.03 |