Table 4 The top 10 UC-MSC research papers with the most citation frequency
Title | First author | Journal | Year | Citations | Citation frequency per year | Main conclusion |
|---|---|---|---|---|---|---|
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue | Kern | Stem Cells | 2006 | 1382 | 115.17 | They compared MSCs derived from umbilical cord blood, bone marrow, and adipose tissue regarding morphology, the success rate of isolating MSCs, colony frequency, expansion potential, multiple differentiation capacity, and immune phenotype |
Isolation of multipotent mesenchymal stem cells from umbilical cord blood | Lee | Blood | 2004 | 819 | 58.5 | They reported a novel method to obtain single cell-derived, clonally expanded MSCs that are of multilineage differentiation potential |
Mesenchymal stem cells in the Wharton’s jelly of the human umbilical cord | Wang | Stem Cells | 2004 | 665 | 47.5 | UC-MSC express matrix receptors (CD44, CD105) and integrin markers (CD29, CD51), and can differentiate into cardiomyocytes |
Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood | Wagner | Experimental Hematology | 2005 | 660 | 50.77 | They provided a foundation for a more reproducible and reliable quality control using genotypic analysis for defining MSCs |
Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood | Bieback | Stem Cells | 2004 | 510 | 36.43 | MSC-like cells can be isolated at high efficacy from full-term UC donations; we regard UC as an additional stem cell source for experimental and potentially clinical purposes |
Searching for alternative sources of postnatal human mesenchymal stem cells: Candidate MSC-like cells from umbilical cord | Romanov | Stem Cells | 2003 | 505 | 33.67 | UC vasculature contains a high number of MSC-like elements forming colonies of fibroblastoid cells that may be successfully expanded in culture |
Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow | Baksh | Stem Cells | 2007 | 457 | 41.55 | They compared HUCPVCs to the “gold standard” bone marrow mesenchymal stromal cells (BMSCs) with respect to their proliferation, differentiation, and transfection capacities |
Adult bone marrow is a rich source of human mesenchymal ‘stem’ cells but umbilical cord and mobilized adult blood are not | Wexler | British Journal of Haematology | 2003 | 384 | 25.6 | Adult BM is a reliable source of functional cultured MSCs, but cord blood and peripheral blood stem cell collections are not |
Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials | Lu | Haematologica | 2006 | 381 | 31.75 | They established a protocol to isolate abundant MSCs from human umbilical cords with a 100% success rate. The comparative study indicates that UC is an excellent alternative to BM as a source of MSCs for cell therapies. |
Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice | Noort | Experimental Hematology | 2002 | 315 | 19.69 | Upon co-transplantation, MSCs, but not irradiated CD34− or B cells, promote engraftment of UCB CD34+ cells in bone marrow, spleen, and blood. |