Fig. 4
From: Embryonic stem cell-derived cardiomyocytes for the treatment of doxorubicin-induced cardiomyopathy
Assessment of electrical activity in DIC mice transplanted with CM-mESCs or placebo. Measures performed before (corresponding to day 0) and after (corresponding to day 42) Dox or saline administration, and after cell or placebo injection (corresponding to days 52 and 77, respectively). a Analysis of heart rate (HR), b PR interval, c P-wave duration, d QRS duration, e QT interval, and f QTc interval. Two-way ANOVA with a Bonferroni post test: *p < 0.05 compared to the control group; #p < 0.05 compared to the Dox + placebo group. Data shown as mean ± standard deviation; n = 18 for the control group, n = 13 for the Dox + placebo group and n = 10 for the Dox + CM-mESC group. Dox doxorubicin, CM-mESC cardiomyocytes derived from mouse embryonic stem cell, d days, QTc corrected QT