TY - JOUR AU - Kim, W. R. AU - Lake, J. R. AU - Smith, J. M. AU - Skeans, M. A. AU - Schladt, D. P. AU - Edwards, E. B. PY - 2017 DA - 2017// TI - OPTN/SRTR 2015 Annual Data Report: Liver JO - Am J Transplant. VL - 17 UR - https://doi.org/10.1111/ajt.14126 DO - 10.1111/ajt.14126 ID - Kim2017 ER - TY - JOUR AU - Dhawan, A. AU - Puppi, J. AU - Hughes, R. D. AU - Mitry, R. R. PY - 2010 DA - 2010// TI - Human hepatocyte transplantation: current experience and future challenges JO - Nat Rev Gastroenterol Hepatol. VL - 7 UR - https://doi.org/10.1038/nrgastro.2010.44 DO - 10.1038/nrgastro.2010.44 ID - Dhawan2010 ER - TY - JOUR AU - Bartlett, D. C. AU - Newsome, P. N. PY - 2015 DA - 2015// TI - Hepatocyte cell therapy in liver disease JO - Expert Rev Gastroenterol Hepatol. VL - 9 UR - https://doi.org/10.1586/17474124.2015.1073106 DO - 10.1586/17474124.2015.1073106 ID - Bartlett2015 ER - TY - JOUR AU - Mitaka, T. PY - 1998 DA - 1998// TI - The current status of primary hepatocyte culture JO - Int J Exp Pathol. VL - 79 UR - https://doi.org/10.1046/j.1365-2613.1998.00083.x DO - 10.1046/j.1365-2613.1998.00083.x ID - Mitaka1998 ER - TY - JOUR AU - Hu, C. AU - Li, L. PY - 2015 DA - 2015// TI - In vitro culture of isolated primary hepatocytes and stem cell-derived hepatocyte-like cells for liver regeneration JO - Protein Cell. VL - 6 UR - https://doi.org/10.1007/s13238-015-0180-2 DO - 10.1007/s13238-015-0180-2 ID - Hu2015 ER - TY - JOUR AU - Szkolnicka, D. AU - Hay, D. C. PY - 2016 DA - 2016// TI - Concise review: advances in generating hepatocytes from pluripotent stem cells for translational medicine JO - Stem Cells. VL - 34 UR - https://doi.org/10.1002/stem.2368 DO - 10.1002/stem.2368 ID - Szkolnicka2016 ER - TY - JOUR AU - Huebert, R. C. AU - Rakela, J. PY - 2014 DA - 2014// TI - Cellular therapy for liver disease JO - Mayo Clin Proc. VL - 89 UR - https://doi.org/10.1016/j.mayocp.2013.10.023 DO - 10.1016/j.mayocp.2013.10.023 ID - Huebert2014 ER - TY - JOUR AU - Bhatia, S. N. AU - Underhill, G. H. AU - Zaret, K. S. AU - Fox, I. J. PY - 2014 DA - 2014// TI - Cell and tissue engineering for liver disease JO - Sci Transl Med VL - 6 UR - https://doi.org/10.1126/scitranslmed.3005975 DO - 10.1126/scitranslmed.3005975 ID - Bhatia2014 ER - TY - JOUR AU - Tolosa, L. AU - Caron, J. AU - Hannoun, Z. AU - Antoni, M. AU - Lopez, S. AU - Burks, D. PY - 2015 DA - 2015// TI - Transplantation of hESC-derived hepatocytes protects mice from liver injury JO - Stem Cell Res Ther. VL - 6 UR - https://doi.org/10.1186/s13287-015-0227-6 DO - 10.1186/s13287-015-0227-6 ID - Tolosa2015 ER - TY - JOUR AU - Chen, Y. F. AU - Tseng, C. Y. AU - Wang, H. W. AU - Kuo, H. C. AU - Yang, V. W. AU - Lee, O. K. PY - 2012 DA - 2012// TI - Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol JO - Hepatology. VL - 55 UR - https://doi.org/10.1002/hep.24790 DO - 10.1002/hep.24790 ID - Chen2012 ER - TY - JOUR AU - Takayama, K. AU - Morisaki, Y. AU - Kuno, S. AU - Nagamoto, Y. AU - Harada, K. AU - Furukawa, N. PY - 2014 DA - 2014// TI - Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes JO - Proc Natl Acad Sci U S A. VL - 111 UR - https://doi.org/10.1073/pnas.1413481111 DO - 10.1073/pnas.1413481111 ID - Takayama2014 ER - TY - JOUR AU - Shlomai, A. AU - Schwartz, R. E. AU - Ramanan, V. AU - Bhatta, A. AU - de Jong, Y. P. AU - Bhatia, S. N. PY - 2014 DA - 2014// TI - Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems JO - Proc Natl Acad Sci U S A. VL - 111 UR - https://doi.org/10.1073/pnas.1412631111 DO - 10.1073/pnas.1412631111 ID - Shlomai2014 ER - TY - JOUR AU - Xia, Y. AU - Carpentier, A. AU - Cheng, X. AU - Block, P. D. AU - Zhao, Y. AU - Zhang, Z. PY - 2017 DA - 2017// TI - Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions JO - J Hepatol. VL - 66 UR - https://doi.org/10.1016/j.jhep.2016.10.009 DO - 10.1016/j.jhep.2016.10.009 ID - Xia2017 ER - TY - JOUR AU - Cai, J. AU - Zhao, Y. AU - Liu, Y. AU - Ye, F. AU - Song, Z. AU - Qin, H. PY - 2007 DA - 2007// TI - Directed differentiation of human embryonic stem cells into functional hepatic cells JO - Hepatology. VL - 45 UR - https://doi.org/10.1002/hep.21582 DO - 10.1002/hep.21582 ID - Cai2007 ER - TY - JOUR AU - Basma, H. AU - Soto Gutiérrez, A. AU - Yannam, G. R. AU - Liu, L. AU - Ito, R. AU - Yamamoto, T. PY - 2009 DA - 2009// TI - Differentiation and transplantation of human embryonic stem cell–derived hepatocytes JO - Gastroenterology. VL - 136 UR - https://doi.org/10.1053/j.gastro.2008.10.047 DO - 10.1053/j.gastro.2008.10.047 ID - Basma2009 ER - TY - JOUR AU - Abe, K. AU - Niwa, H. AU - Iwase, K. AU - Takiguchi, M. AU - Mori, M. AU - Abe, S. I. PY - 1996 DA - 1996// TI - Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies JO - Exp Cell Res. VL - 229 UR - https://doi.org/10.1006/excr.1996.0340 DO - 10.1006/excr.1996.0340 ID - Abe1996 ER - TY - JOUR AU - Takayama, K. AU - Inamura, M. AU - Kawabata, K. AU - Sugawara, M. AU - Kikuchi, K. AU - Higuchi, M. PY - 2012 DA - 2012// TI - Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1alpha transduction JO - J Hepatol. VL - 57 UR - https://doi.org/10.1016/j.jhep.2012.04.038 DO - 10.1016/j.jhep.2012.04.038 ID - Takayama2012 ER - TY - JOUR AU - Takayama, K. AU - Inamura, M. AU - Kawabata, K. AU - Katayama, K. AU - Higuchi, M. AU - Tashiro, K. PY - 2012 DA - 2012// TI - Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4alpha transduction JO - Mol Ther. VL - 20 UR - https://doi.org/10.1038/mt.2011.234 DO - 10.1038/mt.2011.234 ID - Takayama2012 ER - TY - JOUR AU - Si-Tayeb, K. AU - Noto, F. K. AU - Nagaoka, M. AU - Li, J. AU - Battle, M. A. AU - Duris, C. PY - 2010 DA - 2010// TI - Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells JO - Hepatology. VL - 51 UR - https://doi.org/10.1002/hep.23354 DO - 10.1002/hep.23354 ID - Si-Tayeb2010 ER - TY - JOUR AU - Sullivan, G. J. AU - Hay, D. C. AU - Park, I. H. AU - Fletcher, J. AU - Hannoun, Z. AU - Payne, C. M. PY - 2010 DA - 2010// TI - Generation of functional human hepatic endoderm from human induced pluripotent stem cells JO - Hepatology. VL - 51 UR - https://doi.org/10.1002/hep.23335 DO - 10.1002/hep.23335 ID - Sullivan2010 ER - TY - JOUR AU - Song, Z. AU - Cai, J. AU - Liu, Y. AU - Zhao, D. AU - Yong, J. AU - Duo, S. PY - 2009 DA - 2009// TI - Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells JO - Cell Res. VL - 19 UR - https://doi.org/10.1038/cr.2009.107 DO - 10.1038/cr.2009.107 ID - Song2009 ER - TY - JOUR AU - Hay, D. C. AU - Zhao, D. AU - Fletcher, J. AU - Hewitt, Z. A. AU - McLean, D. AU - Urruticoechea-Uriguen, A. PY - 2008 DA - 2008// TI - Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo JO - Stem Cells. VL - 26 UR - https://doi.org/10.1634/stemcells.2007-0718 DO - 10.1634/stemcells.2007-0718 ID - Hay2008 ER - TY - JOUR AU - Agarwal, S. AU - Holton, K. L. AU - Lanza, R. PY - 2008 DA - 2008// TI - Efficient differentiation of functional hepatocytes from human embryonic stem cells JO - Stem Cells. VL - 26 UR - https://doi.org/10.1634/stemcells.2007-1102 DO - 10.1634/stemcells.2007-1102 ID - Agarwal2008 ER - TY - JOUR AU - Kajiwara, M. AU - Aoi, T. AU - Okita, K. AU - Takahashi, R. AU - Inoue, H. AU - Takayama, N. PY - 2012 DA - 2012// TI - Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells JO - Proc Natl Acad Sci U S A. VL - 109 UR - https://doi.org/10.1073/pnas.1209979109 DO - 10.1073/pnas.1209979109 ID - Kajiwara2012 ER - TY - JOUR AU - Jozefczuk, J. AU - Prigione, A. AU - Chavez, L. AU - Adjaye, J. PY - 2011 DA - 2011// TI - Comparative analysis of human embryonic stem cell and induced pluripotent stem cell-derived hepatocyte-like cells reveals current drawbacks and possible strategies for improved differentiation JO - Stem Cells Dev. VL - 20 UR - https://doi.org/10.1089/scd.2010.0361 DO - 10.1089/scd.2010.0361 ID - Jozefczuk2011 ER - TY - JOUR AU - Hannan, N. R. AU - Segeritz, C. P. AU - Touboul, T. AU - Vallier, L. PY - 2013 DA - 2013// TI - Production of hepatocyte-like cells from human pluripotent stem cells JO - Nat Protoc. VL - 8 UR - https://doi.org/10.1038/nprot.2012.153 DO - 10.1038/nprot.2012.153 ID - Hannan2013 ER - TY - JOUR AU - Li, W. AU - Li, K. AU - Wei, W. AU - Ding, S. PY - 2013 DA - 2013// TI - Chemical approaches to stem cell biology and therapeutics JO - Cell Stem Cell. VL - 13 UR - https://doi.org/10.1016/j.stem.2013.08.002 DO - 10.1016/j.stem.2013.08.002 ID - Li2013 ER - TY - JOUR AU - Liu, K. AU - Yu, C. AU - Xie, M. AU - Li, K. AU - Ding, S. PY - 2016 DA - 2016// TI - Chemical modulation of cell fate in stem cell therapeutics and regenerative medicine JO - Cell Chem Biol. VL - 23 UR - https://doi.org/10.1016/j.chembiol.2016.07.007 DO - 10.1016/j.chembiol.2016.07.007 ID - Liu2016 ER - TY - JOUR AU - Zhang, Y. AU - Li, W. AU - Laurent, T. AU - Ding, S. PY - 2013 DA - 2013// TI - Small molecules, big roles - the chemical manipulation of stem cell fate and somatic cell reprogramming JO - J Cell Sci. VL - 125 UR - https://doi.org/10.1242/jcs.096032 DO - 10.1242/jcs.096032 ID - Zhang2013 ER - TY - JOUR AU - Zhu, S. AU - Rezvani, M. AU - Harbell, J. AU - Mattis, A. N. AU - Wolfe, A. R. AU - Benet, L. Z. PY - 2014 DA - 2014// TI - Mouse liver repopulation with hepatocytes generated from human fibroblasts JO - Nature. VL - 508 UR - https://doi.org/10.1038/nature13020 DO - 10.1038/nature13020 ID - Zhu2014 ER - TY - JOUR AU - Hay, D. C. AU - Fletcher, J. AU - Payne, C. AU - Terrace, J. D. AU - Gallagher, R. C. AU - Snoeys, J. PY - 2008 DA - 2008// TI - Highly efficient differentiation of hESCs to functional hepatic endoderm requires Activin A and Wnt3a signaling JO - Proc Natl Acad Sci U S A. VL - 105 UR - https://doi.org/10.1073/pnas.0806522105 DO - 10.1073/pnas.0806522105 ID - Hay2008 ER - TY - JOUR AU - Touboul, T. AU - Chen, S. AU - Mora-Castilla, S. AU - Sabatini, K. AU - Tukey, R. H. PY - 2016 DA - 2016// TI - Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes JO - J Hepatol. VL - 64 UR - https://doi.org/10.1016/j.jhep.2016.02.028 DO - 10.1016/j.jhep.2016.02.028 ID - Touboul2016 ER - TY - JOUR AU - Bone, H. K. AU - Nelson, A. S. AU - Goldring, C. E. AU - Tosh, D. AU - Welham, M. J. PY - 2011 DA - 2011// TI - A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3 JO - J Cell Sci. VL - 124 UR - https://doi.org/10.1242/jcs.081679 DO - 10.1242/jcs.081679 ID - Bone2011 ER - TY - JOUR AU - Siller, R. AU - Greenhough, S. AU - Naumovska, E. AU - Sullivan, G. J. PY - 2015 DA - 2015// TI - Small-molecule-driven hepatocyte differentiation of human pluripotent stem cells JO - Stem Cell Reports. VL - 4 UR - https://doi.org/10.1016/j.stemcr.2015.04.001 DO - 10.1016/j.stemcr.2015.04.001 ID - Siller2015 ER - TY - JOUR AU - Ke, Q. AU - Li, L. AU - Cai, B. AU - Liu, C. AU - Yang, Y. AU - Gao, Y. PY - 2013 DA - 2013// TI - Connexin 43 is involved in the generation of human-induced pluripotent stem cells JO - Hum Mol Genet. VL - 22 UR - https://doi.org/10.1093/hmg/ddt074 DO - 10.1093/hmg/ddt074 ID - Ke2013 ER - TY - JOUR AU - Ke, Q. AU - Li, L. AU - Yao, X. AU - Lai, X. AU - Cai, B. AU - Chen, H. PY - 2017 DA - 2017// TI - Enhanced generation of human induced pluripotent stem cells by ectopic expression of Connexin 45 JO - Sci Rep. VL - 7 UR - https://doi.org/10.1038/s41598-017-00523-y DO - 10.1038/s41598-017-00523-y ID - Ke2017 ER - TY - JOUR AU - Cheng, F. AU - Ke, Q. AU - Chen, F. AU - Cai, B. AU - Gao, Y. AU - Ye, C. PY - 2012 DA - 2012// TI - Protecting against wayward human induced pluripotent stem cells with a suicide gene JO - Biomaterials. VL - 33 UR - https://doi.org/10.1016/j.biomaterials.2012.01.023 DO - 10.1016/j.biomaterials.2012.01.023 ID - Cheng2012 ER - TY - JOUR AU - Engert, S. AU - Burtscher, I. AU - Liao, W. P. AU - Dulev, S. AU - Schotta, G. AU - Lickert, H. PY - 2013 DA - 2013// TI - Wnt/beta-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse JO - Development. VL - 140 UR - https://doi.org/10.1242/dev.088765 DO - 10.1242/dev.088765 ID - Engert2013 ER - TY - JOUR AU - Cao, N. AU - Liang, H. AU - Huang, J. AU - Wang, J. AU - Chen, Y. AU - Chen, Z. PY - 2013 DA - 2013// TI - Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions JO - Cell Res. VL - 23 UR - https://doi.org/10.1038/cr.2013.102 DO - 10.1038/cr.2013.102 ID - Cao2013 ER - TY - JOUR AU - Li, W. AU - Wang, D. AU - Qin, J. AU - Liu, C. AU - Zhang, Q. AU - Zhang, X. PY - 2010 DA - 2010// TI - Generation of functional hepatocytes from mouse induced pluripotent stem cells JO - J Cell Physiol. VL - 222 ID - Li2010 ER - TY - JOUR AU - Shan, J. AU - Schwartz, R. E. AU - Ross, N. T. AU - Logan, D. J. AU - Thomas, D. AU - Duncan, S. A. PY - 2013 DA - 2013// TI - Identification of small molecules for human hepatocyte expansion and iPS differentiation JO - Nat Chem Biol. VL - 9 UR - https://doi.org/10.1038/nchembio.1270 DO - 10.1038/nchembio.1270 ID - Shan2013 ER - TY - JOUR AU - Loh, K. M. AU - Ang, L. T. AU - Zhang, J. AU - Kumar, V. AU - Ang, J. AU - Auyeong, J. Q. PY - 2014 DA - 2014// TI - Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations JO - Cell Stem Cell. VL - 14 UR - https://doi.org/10.1016/j.stem.2013.12.007 DO - 10.1016/j.stem.2013.12.007 ID - Loh2014 ER - TY - JOUR AU - Gordillo, M. AU - Evans, T. AU - Gouon-Evans, V. PY - 2015 DA - 2015// TI - Orchestrating liver development JO - Development. VL - 142 UR - https://doi.org/10.1242/dev.114215 DO - 10.1242/dev.114215 ID - Gordillo2015 ER - TY - JOUR AU - Si-Tayeb, K. AU - Lemaigre, F. P. AU - Duncan, S. A. PY - 2010 DA - 2010// TI - Organogenesis and development of the liver JO - Dev Cell. VL - 18 UR - https://doi.org/10.1016/j.devcel.2010.01.011 DO - 10.1016/j.devcel.2010.01.011 ID - Si-Tayeb2010 ER - TY - JOUR AU - Tasnim, F. AU - Phan, D. AU - Toh, Y. C. AU - Yu, H. PY - 2015 DA - 2015// TI - Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules JO - Biomaterials. VL - 70 UR - https://doi.org/10.1016/j.biomaterials.2015.08.002 DO - 10.1016/j.biomaterials.2015.08.002 ID - Tasnim2015 ER - TY - JOUR AU - Li, W. AU - You, P. AU - Wei, Q. AU - Li, Y. AU - Fu, X. AU - Ding, X. PY - 2007 DA - 2007// TI - Hepatic differentiation and transcriptional profile of the mouse liver epithelial progenitor cells (LEPCs) under the induction of sodium butyrate JO - Front Biosci. VL - 12 UR - https://doi.org/10.2741/2181 DO - 10.2741/2181 ID - Li2007 ER - TY - JOUR AU - Yang, J. AU - Wang, Y. AU - Zhou, T. AU - Wong, L. Y. AU - Tian, X. Y. AU - Hong, X. PY - 2017 DA - 2017// TI - Generation of human liver chimeric mice with hepatocytes from familial hypercholesterolemia induced pluripotent stem cells JO - Stem Cell Reports. VL - 8 UR - https://doi.org/10.1016/j.stemcr.2017.01.027 DO - 10.1016/j.stemcr.2017.01.027 ID - Yang2017 ER - TY - JOUR AU - Huang, P. AU - Zhang, L. AU - Gao, Y. AU - He, Z. AU - Yao, D. AU - Wu, Z. PY - 2014 DA - 2014// TI - Direct reprogramming of human fibroblasts to functional and expandable hepatocytes JO - Cell Stem Cell. VL - 14 UR - https://doi.org/10.1016/j.stem.2014.01.003 DO - 10.1016/j.stem.2014.01.003 ID - Huang2014 ER -