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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming

Fig. 4

DNA methylation profiling of DiPS and AiPS cell lines in comparison to their parental cells. a Heatmap of the methylation ratio (beta-value) of global probe sets for genes in the dental-derived somatic parental (L1, UM), DiPS (L1 iPS, UM iPS), and H1 ES cells. Duplicates for each cell line. b Heatmap of the methylation ratio (beta-value) of global probe sets for genes in the adipose-derived somatic parental (PC, SP, L), AiPS (PC iPS, SP iPS, L iPS), and H1 hES cells. Duplicates for each cell line. c Heatmap representing classic pluripotent genes in parental DPSCs and ASCs with respect to their resultant iPS lines and H1 hES cells. The methylation ratio is averaged across all probes for each gene and across all samples in the same group. AiPS adipose-derived stem cell-derived induced pluripotent stem, ASC adipose-derived stem cell, DiPS dental pulp stem cell-derived induced pluripotent stem, DPSC dental pulp stem cell, ES embryonic stem, iPS induced pluripotent stem

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