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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model

Fig. 3

Transplantation of islet-1 human mesenchymal stem cells (ISL1-hMSCs) reduced cardiac infarct size and fibrotic size in a myocardial infarction (MI) model. (a) Representative images of infarct size. Representative images (b) and quantification (c) of the fibrotic area in the infarct border zone by Masson’s trichrome staining at 4 weeks post-MI. Data are presented as the mean ± SD, n = 8; *p < 0.05, vs. sham; #p < 0.05 vs. MI + phosphate-buffered saline (PBS); &p < 0.05 vs. MI + ISL1-hMSCs. Scale bar = 50 μm. Ctrl control

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Stem Cell Research & Therapy

ISSN: 1757-6512