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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model

Fig. 4

Transplantation of islet-1 human mesenchymal stem cells (ISL1-hMSCs) increased angiogenesis and reduced apoptosis. Representative images (a) and quantification (b) of capillary density in the infarct border zone at 4 weeks post-myocardial infarct (MI) detected by CD31 staining. Representative images (c) and quantification (d) of TUNEL-positive cells in the infarct border. Data are presented as the mean ± SD, n = 8; *p < 0.05, vs. sham; #p < 0.05 vs. MI + phosphate-buffered saline (PBS); &p < 0.05 vs. MI + ISL1-hMSCs. Scale bar = 50 μm. Ctrl control

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