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Table 4 Significant findings on histologic section assessment

From: Radial shockwave treatment promotes human mesenchymal stem cell self-renewal and enhances cartilage healing

Histologic category Sham S only S + untMSC S + tMSC P value
Surface/superficial architecture 23 ± 2 55 ± 3 83 ± 6 98 ± 3 0.01**
Repair–host integration 19 ± 7 62 ± 18 79 ± 13 87 ± 11 0.04*
Basal integration 25 ± 3 69 ± 5 88 ± 3 93 ± 4 0.05*
Overall assessment 27 ± 2 65 ± 8 83 ± 8 93 ± 6 0.03*
Matrix staining (metachromasia) 12 ± 4 47 ± 12 82 ± 5 98 ± 3 0.01**
Subchondral bone vascularization 33 ± 9 67 ± 11 83 ± 10 84 ± 8 0.2
Type II collagen 17 ± 2 71 ± 15 90 ± 5 93 ± 3 0.1
  1. Data presented as mean ± standard deviation. The International Cartilage Repair Society II scoring system was modified to assess cartilage repair and vascularization in subchondral bone. A score of 100 indicates normal and 0 represents complete loss of normal architecture. Student’s t test applied to compare the S + untMSC and S + tMSC group
  2. Sham sham surgery group, S only scaffold only group, S + untMSC scaffold + untreated MSC group, S + tMSC scaffold + treated MSC group, MSC mesenchymal stem cell
  3. *Statistically significant difference compared with control groups, P < 0.05
  4. **Statistically significant difference compared with control groups, P < 0.01