Histologic category | Sham | S only | S + untMSC | S + tMSC | P value |
---|---|---|---|---|---|
Surface/superficial architecture | 23 ± 2 | 55 ± 3 | 83 ± 6 | 98 ± 3 | 0.01** |
Repair–host integration | 19 ± 7 | 62 ± 18 | 79 ± 13 | 87 ± 11 | 0.04* |
Basal integration | 25 ± 3 | 69 ± 5 | 88 ± 3 | 93 ± 4 | 0.05* |
Overall assessment | 27 ± 2 | 65 ± 8 | 83 ± 8 | 93 ± 6 | 0.03* |
Matrix staining (metachromasia) | 12 ± 4 | 47 ± 12 | 82 ± 5 | 98 ± 3 | 0.01** |
Subchondral bone vascularization | 33 ± 9 | 67 ± 11 | 83 ± 10 | 84 ± 8 | 0.2 |
Type II collagen | 17 ± 2 | 71 ± 15 | 90 ± 5 | 93 ± 3 | 0.1 |