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Table 4 Significant findings on histologic section assessment

From: Radial shockwave treatment promotes human mesenchymal stem cell self-renewal and enhances cartilage healing

Histologic category

Sham

S only

S + untMSC

S + tMSC

P value

Surface/superficial architecture

23 ± 2

55 ± 3

83 ± 6

98 ± 3

0.01**

Repair–host integration

19 ± 7

62 ± 18

79 ± 13

87 ± 11

0.04*

Basal integration

25 ± 3

69 ± 5

88 ± 3

93 ± 4

0.05*

Overall assessment

27 ± 2

65 ± 8

83 ± 8

93 ± 6

0.03*

Matrix staining (metachromasia)

12 ± 4

47 ± 12

82 ± 5

98 ± 3

0.01**

Subchondral bone vascularization

33 ± 9

67 ± 11

83 ± 10

84 ± 8

0.2

Type II collagen

17 ± 2

71 ± 15

90 ± 5

93 ± 3

0.1

  1. Data presented as mean ± standard deviation. The International Cartilage Repair Society II scoring system was modified to assess cartilage repair and vascularization in subchondral bone. A score of 100 indicates normal and 0 represents complete loss of normal architecture. Student’s t test applied to compare the S + untMSC and S + tMSC group
  2. Sham sham surgery group, S only scaffold only group, S + untMSC scaffold + untreated MSC group, S + tMSC scaffold + treated MSC group, MSC mesenchymal stem cell
  3. *Statistically significant difference compared with control groups, P < 0.05
  4. **Statistically significant difference compared with control groups, P < 0.01