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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Engineering a multicellular vascular niche to model hematopoietic cell trafficking

Fig. 5

When perfused after monocytes, CD34+ cells preferentially adhere in endothelial cell (EC)-only and HS27a-modified vessels. a Healthy CD34+ cells (white) are perfused 24 h after monocytes (red) in each vessel type. Healthy CD34+ cells and monocytes appear to cluster together. Blue = nuclei. b Locations of healthy CD34+ cells are seen relative to vessel wall (yellow dotted line). Scale bars = 100 μm. c Quantification of CD34+ cell adhesion and migration in vessels. *p < 0.05, **p < 0.01. HSPC hematopoietic stem and progenitor cell

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