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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Engineering a multicellular vascular niche to model hematopoietic cell trafficking

Fig. 7

Leukemic cells perfused after monocytes do not adhere based on stromal cues. a Leukemic CD34+ cells perfused after monocytes in unmodified, HS5-, and HS27a-modified vessels. Blue = nuclei. b Adhesion and migration of leukemic cells are shown in relation to the vessel walls (yellow dotted lines). Scale bars = 100 μm. c Quantification of monocyte and leukemic CD34+ cell adhesion and migration. *p < 0.05. EC endothelial cell

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