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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage

Fig. 5

Effect of DOT1L knockdown on (a) KIND1 and (b) HES3 cell morphology on different days of differentiation. Both KIND1 and HES3 cells displayed mesenchymal morphology in their wild-type and nontarget siRNA-treated state characteristic of the mesodermal to cardiac differentiation as compared to the impaired cardiac differentiation pattern noted post DOT1L knockdown. Magnification 10×. D day

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Stem Cell Research & Therapy

ISSN: 1757-6512