Fig. 9From: Impact of bone marrow mesenchymal stem cell immunomodulation on the osteogenic effects of laponitea The gross view and H&E staining of the defects filled with laponite (Lap) and Lap + rat bone marrow mesenchymal stem cells (Lap+rBMSCs). b Immunohistochemical staining of the surface markers for M1 macrophages (CD11c and CCR-7) and M2 macrophages (CD163). The experiment was repeated three times with similar results. The arrows show multinucleated giant cells. F fibrous tissue, NB newly formed bone, OB old boneBack to article page