From: Efficient induction of functional ameloblasts from human keratinocyte stem cells
Protein in culture (h) | Protein beads in recombinant | Number of recombinants | Number of tooth formations | Ratio of tooth formation (%) | Number of ameloblastic differentiations | Ratio of ameloblastic differentiation (%) | ||
---|---|---|---|---|---|---|---|---|
FGF8 | SHH | FGF8 | SHH | |||||
– | – | + | + | 25 | 12 | 48.0 | 8 | 66.7 |
18 | – | + | + | 11 | 5 | 45.5 | 5 | 100 |
– | 18 | – | – | 10 | 1 | 10.0 | 1 | 100 |
18 | 18 | + | + | 17 | 9 | 52.9 | 9 | 100 |
36 | 36 | + | + | 13 | 9 | 69.2 | 9 | 100 |