Fig. 3
From: Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells
Metabolome analysis and SAGE. a PCA of normalized metabolic data obtained from MSCs 48 h after AAP addition and controls (0 mM). Percentage values indicated on the axes represent the contribution rate of the first (PC1) and second (PC2) principal components to the total amount of variation. b Heat map of the hierarchical cluster analysis. The columns indicate experimental groups of MSCs with addition of AAP (1 mM), and controls (0 mM). The rows show the normalized levels of each metabolite. The dendrogram for each heatmap shows the relatedness of the normalized metabolite level patterns. c Changes in carnitine expression in MSCs cultured in the presence of AAP. d Changes in various ribonucleotides in MSCs cultured in the presence of AAP. e Changes in metabolites associated with TCA in MSCs cultured in the presence of AAP. **p < 0.01