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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Dental pulp stem cells used to deliver the anticancer drug paclitaxel

Fig. 5

Viability of DPSCs after releasing PTX. a Integrated Raman intensities in 2800–3000 cm–1 region of cells. b Raman reconstruction of a, using KMCA to detect intracellular PTX (pink spots). c Correlation map and correlation coefficient between whole cell image and image of cytochrome c. Best correlation obtained for red pixels (indicated by black arrows): region with highest correlation between reference spectrum of cytochrome c and their spectra in cells. Region with no correlation to cytochrome c is due to PBS buffer (blue region). d Mitochondrial cluster (black) obtained from KMCA. e Mitochondrial cluster overlapped with correlation map of cytochrome c. All positions corresponding to cytochrome c are covered, indicating localization of cytochrome c inside mitochondria

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