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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice

Fig. 3

Intraperitoneally administered canine adipose tissue-derived mesenchymal stem cells (cAT-MSCs) do not migrate into the colon. a Standard curves for evaluating the migratory ability of intraperitoneally (i.p.) injected cells were generated by administering serial dilutions of cAT-MSCs to the mouse heart, lung, liver, spleen, kidney, and colon. b–d The percentage of infused cAT-MSCs in the organs was evaluated b at 2 h, c at 1 day, and d at 3 days after cell administration. Results are presented as the mean ± standard deviation of the data obtained in three independent experiments. nd, not detected; siCTL-cAT-MSC, cAT-MSCs transfected with scrambled small interfering RNA; siTSG6-cAT-MSC, cAT-MSCs transfected with TSG-6 tumor necrosis factor-α-induced gene/protein-6 small interfering RNA

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Stem Cell Research & Therapy

ISSN: 1757-6512