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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease

Fig. 2

Quantification of transcript levels of genes described to be significantly upregulated in skeletal muscle of SOD1G93A mice at late phases of the disease (120 days). a Fold-change in expression of Col19a1, Gsr, Snx10, Calm1 and Mef2c. b Downregulation of Sln, Impa1, Nnt, Mt2 and Ankrd1. c Transcript levels of Pax7 and myogenic regulatory factors (Myod, Myf5, Myog). Results shown as fold-change in BMC-treated SOD1G93A mice muscles (dark gray bars) relative to sham-injected muscles (light gray bars). *p < 0.05; **p < 0.01; ***p < 0.001

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