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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease

Fig. 3

Spinal cord motoneuron (MN) counting and neuromuscular state after BMC transplantation (at 120 days). a DiI-labeled MNs (red) in the spinal cord, nuclei stained with DAPI (blue). b 40× image of DiI-stained MN. c Right: number of MNs in mice treated with bone marrow on one hind limb versus the contralateral limb. *p < 0.05. Error bars indicate SEM. n = 6 mice. Left: number of MNs in the spinal cord of sham-injected mice. Error bars indicate SEM. n = 5. d Chrna1, Rrad and NogoA transcript levels in BMC-treated mice relative to sham-injected mice. SH = Sham-operated; TR = Treated. *p < 0.05; **p < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512