Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Expression profiling of cell-intrinsic regulators in the process of differentiation of human iPSCs into retinal lineages

Fig. 3

Microarray analysis of transcriptomes of OV, RGC and RPE samples derived from hiPSCs. a Principal component analysis (PCA) of hiPSC, OV, RGC and RPE biological replicate samples. b Pearson correlation matrix of hiPSC, OV, RGC and RPE biological replicate samples. c Venn diagram demonstrating number of common and unique differentially overexpressed genes in OV, RGC and RPE samples compared to original hiPSCs according to criteria of linear fold-change > 2 and p < 0.01. Text boxes show top 20 DEGs sorted by fold-change in each sample. d Venn diagram demonstrating number of common and unique differentially underexpressed genes in OV, RGC and RPE samples compared to original hiPSCs according to criteria of linear fold-change > 2 and p < 0.01. Text boxes show top 20 DEGs sorted by fold-change in each sample. hiPSC human induced pluripotent stem cell, OV optic vesicle, RGC retinal ganglion cell, RPE retinal pigment epithelium

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512