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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Platelet-rich plasma enhances the proliferation of human adipose stem cells through multiple signaling pathways

Fig. 2

PDGF-BB mediated the stimulatory effect of PRP. Cells were incubated with reagents at indicated concentrations in serum-free DMEM for 48 h. Cell proliferation assessed with Cell Counting Kit-8. a PDGF-BB enhanced hASC proliferation in a dose-dependent manner (n = 7). b Effect of imatinib (5 μM) and sorafenib (5 μM) on PRP-dependent proliferation of hASCs (n = 7). c Effect of imatinib (5 μM) and sorafenib (5 μM) on PDGF-BB-dependent proliferation of hASCs (n = 7). d Anti-PDGF antibody inhibited PRP-stimulated proliferation of hASCs (n = 4). *P < 0.05. PDGF platelet-derived growth factor, PRP platelet-rich plasma

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