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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches

Fig. 1

Proliferative behavior of hMuStem cellsFBS cultured in vitro in HS-supplemented or hPL-supplemented medium. a hMuStem cellsFBS (n = 3, donors #1–#3) cultured for 14 days in growth medium (GM) supplemented with either 10% FBS, 10% HS, or 10% hPL. Proliferation rates determined as mean cumulative population doubling (CPD) number, expressed as percentage of corresponding values obtained for FBS-GM (*p < 0.05, Friedman test). b hMuStem cellsHS (n = 3, donors #4–#6) cultured for 6 days in GM supplemented with either 10% HS or 10% hPL, in presence or absence of 10 ng/ml bFGF. Proliferation rates determined as CPD (***p < 0.001, LME model followed by Tukey’s post-hoc test). FBS fetal bovine serum, HS human serum, hPL human platelet lysate, bFGF basic fibroblast growth factor

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